RNA Interference of Human Papillomavirus Type 18 E6 and E7 Induces Senescence in HeLa Cells

The human papillomavirus oncoproteins E6 and E7 promote cell proliferation and contribute to carcinogenesis by interfering with the activities of cellular tumor suppressors. We used a small interfering RNA molecule targeting the E7 region of the bicistronic E6 and E7 mRNA to induce RNA interference,...

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Pubblicato in:	J Virol
Autori principali:	Hall, Allison H. S., Alexander, Kenneth A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Transformation and Oncogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12719599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.10.6066-6069.2003
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