RNA Interference of Human Papillomavirus Type 18 E6 and E7 Induces Senescence in HeLa Cells

The human papillomavirus oncoproteins E6 and E7 promote cell proliferation and contribute to carcinogenesis by interfering with the activities of cellular tumor suppressors. We used a small interfering RNA molecule targeting the E7 region of the bicistronic E6 and E7 mRNA to induce RNA interference,...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hall, Allison H. S., Alexander, Kenneth A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12719599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.10.6066-6069.2003
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