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Positive Regulation of CXCR4 Expression and Signaling by Interleukin-7 in CD4(+) Mature Thymocytes Correlates with Their Capacity To Favor Human Immunodeficiency X4 Virus Replication

The emergence of X4 human immunodeficiency virus type 1 (HIV-1) variants in infected individuals is associated with poor prognosis. One of the possible causes of this emergence might be the selection of X4 variants in some specific tissue compartment. We demonstrate that the thymic microenvironment...

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Autori principali: Schmitt, Nathalie, Chêne, Laurent, Boutolleau, David, Nugeyre, Marie-Thérèse, Guillemard, Eric, Versmisse, Pierre, Jacquemot, Catherine, Barré-Sinoussi, Françoise, Israël, Nicole
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC154045/
https://ncbi.nlm.nih.gov/pubmed/12719571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5784-5793.2003
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