Positive Regulation of CXCR4 Expression and Signaling by Interleukin-7 in CD4(+) Mature Thymocytes Correlates with Their Capacity To Favor Human Immunodeficiency X4 Virus Replication

The emergence of X4 human immunodeficiency virus type 1 (HIV-1) variants in infected individuals is associated with poor prognosis. One of the possible causes of this emergence might be the selection of X4 variants in some specific tissue compartment. We demonstrate that the thymic microenvironment...

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Detalhes bibliográficos
Main Authors: Schmitt, Nathalie, Chêne, Laurent, Boutolleau, David, Nugeyre, Marie-Thérèse, Guillemard, Eric, Versmisse, Pierre, Jacquemot, Catherine, Barré-Sinoussi, Françoise, Israël, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154045/
https://ncbi.nlm.nih.gov/pubmed/12719571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5784-5793.2003
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