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Human Herpesvirus 8-Encoded vGPCR Activates Nuclear Factor of Activated T Cells and Collaborates with Human Immunodeficiency Virus Type 1 Tat

Human herpesvirus 8 (HHV-8), the etiologic agent of Kaposi's sarcoma (KS), encodes a chemokine receptor homologue, the viral G protein-coupled receptor (vGPCR), that has been implicated in KS pathogenesis. Expression of vGPCR constitutively activates several signaling pathways, including NF-κB,...

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Detalhes bibliográficos
Main Authors: Pati, Shibani, Foulke, Jr., James S., Barabitskaya, Oxana, Kim, Jynho, Nair, B. C., Hone, David, Smart, Jennifer, Feldman, Ricardo A., Reitz, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154031/
https://ncbi.nlm.nih.gov/pubmed/12719569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.5759-5773.2003
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