Intranasal Vaccination Using Interleukin-12 and Cholera Toxin Subunit B as Adjuvants To Enhance Mucosal and Systemic Immunity to Human Immunodeficiency Virus Type 1 Glycoproteins

We have investigated the induction of protective mucosal immunity to human immunodeficiency virus type 1 (HIV-1) isolate 89.6 by intranasal (i.n.) immunization of mice with gp120 and gp140 together with interleukin-12 (IL-12) and cholera toxin subunit B (CTB) as adjuvants. It was found that both IL-...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Albu, Diana I., Jones-Trower, Agnes, Woron, Amy M., Stellrecht, Kathleen, Broder, Christopher C., Metzger, Dennis W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Vaccines and Antiviral Agents
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12719551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.10.5589-5597.2003
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