Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP

Interferon-γ (IFN-γ) is critical for defense against pathogens, but the molecules that mediate its antimicrobial responses are largely unknown. IGTP is the prototype for a family of IFN-γ-regulated genes that encode 48-kDa GTP-binding proteins that localize to the endoplasmic reticulum. We have gene...

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Main Authors: Taylor, Gregory A., Collazo, Carmen M., Yap, George S., Nguyen, Khuong, Gregorio, Theresa A., Taylor, Lynn S., Eagleson, Bryn, Secrest, Lisa, Southon, Eileen A., Reid, Susan W., Tessarollo, Lino, Bray, Mike, McVicar, Dan W., Komschlies, Kristin L., Young, Howard A., Biron, Christine A., Sher, Alan, Vande Woude, George F.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC15402/
https://ncbi.nlm.nih.gov/pubmed/10639151
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