טוען...

Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a Gamma-interferon-inducible lysosomal thiol reductase (GILT)

Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin, but the mechanism o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Arunachalam, Balasubramanian, Phan, Uyen T., Geuze, Hans J., Cresswell, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC15401/
https://ncbi.nlm.nih.gov/pubmed/10639150
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!