Induction of Broad and Potent Anti-Human Immunodeficiency Virus Immune Responses in Rhesus Macaques by Priming with a DNA Vaccine and Boosting with Protein-Adsorbed Polylactide Coglycolide Microparticles

Several vaccine technologies were evaluated for their abilities to induce anti-human immunodeficiency virus Gag immune responses in rhesus macaques. While no vaccine alone was able to induce broad and strong immune responses, these were achieved by priming with Gag DNA and boosting with Gag protein...

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Main Authors: Otten, Gillis, Schaefer, Mary, Greer, Catherine, Calderon-Cacia, Maria, Coit, Doris, Kazzaz, Jina, Medina-Selby, Angelica, Selby, Mark, Singh, Manmohan, Ugozzoli, Mildred, zur Megede, Jan, Barnett, Susan W., O'Hagan, Derek, Donnelly, John, Ulmer, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154004/
https://ncbi.nlm.nih.gov/pubmed/12719603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.10.6087-6092.2003
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