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Specific Cleavages by RNase H Facilitate Initiation of Plus-Strand RNA Synthesis by Moloney Murine Leukemia Virus

Successful generation, extension, and removal of the plus-strand primer is integral to reverse transcription. For Moloney murine leukemia virus, primer removal at the RNA/DNA junction leaves the 3′ terminus of the plus-strand primer abutting the downstream plus-strand DNA, but this 3′ terminus is no...

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Detalhes bibliográficos
Main Authors: Schultz, Sharon J., Zhang, Miaohua, Champoux, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153992/
https://ncbi.nlm.nih.gov/pubmed/12692229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5275-5285.2003
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