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Distinct Roles of the Adenovirus E4 ORF3 Protein in Viral DNA Replication and Inhibition of Genome Concatenation

Adenovirus early proteins E4 ORF3 and E4 ORF6 have complementary functions during viral infection. Both proteins facilitate efficient viral DNA replication, late protein expression, and prevention of concatenation of viral genomes. Additionally, E4 ORF6 is involved in the shutoff of the host cell pr...

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Vydáno v:J Virol
Hlavní autoři: Evans, Jared D., Hearing, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692231/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.9.5295-5304.2003
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