Distinct Roles of the Adenovirus E4 ORF3 Protein in Viral DNA Replication and Inhibition of Genome Concatenation

Adenovirus early proteins E4 ORF3 and E4 ORF6 have complementary functions during viral infection. Both proteins facilitate efficient viral DNA replication, late protein expression, and prevention of concatenation of viral genomes. Additionally, E4 ORF6 is involved in the shutoff of the host cell pr...

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Publié dans:	J Virol
Auteurs principaux:	Evans, Jared D., Hearing, Patrick
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2003
Sujets:	Virus-Cell Interactions
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.9.5295-5304.2003
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