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Roles for Endocytosis and Low pH in Herpes Simplex Virus Entry into HeLa and Chinese Hamster Ovary Cells

Herpes simplex virus (HSV) infection of many cultured cells, e.g., Vero cells, can be initiated by receptor binding and pH-neutral fusion with the cell surface. Here we report that a major pathway for HSV entry into the HeLa and CHO-K1 cell lines is dependent on endocytosis and exposure to a low pH....

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Bibliographic Details
Main Authors: Nicola, Anthony V., McEvoy, Anna M., Straus, Stephen E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153978/
https://ncbi.nlm.nih.gov/pubmed/12692234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5324-5332.2003
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