Entry of Herpes Simplex Virus Type 1 into Primary Sensory Neurons In Vitro Is Mediated by Nectin-1/HveC

Primary cultures of rat and mouse sensory neurons were used to study the entry of herpes simplex virus type 1 (HSV-1). Soluble, truncated nectin-1 but not HveA prevented viral entry. Antibodies against nectin-1 also blocked infection of rat neurons. These results indicate that nectin-1 is the primar...

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Detalhes bibliográficos
Main Authors: Richart, Sarah M., Simpson, Scott A., Krummenacher, Claude, Whitbeck, J. Charles, Pizer, Lewis I., Cohen, Gary H., Eisenberg, Roselyn J., Wilcox, Christine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149788/
https://ncbi.nlm.nih.gov/pubmed/12584355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3307-3311.2003
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