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Construction and Characterization of an Attenuated Purine Auxotroph in a Francisella tularensis Live Vaccine Strain
Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. It is capable of escaping from the phagosome, replicating to high numbers in the cytosol, and inducing apoptosis in macrophages of a variety of hosts. F. tularensis has received significant atte...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1539594/ https://ncbi.nlm.nih.gov/pubmed/16861631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00666-06 |
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