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Construction and Characterization of an Attenuated Purine Auxotroph in a Francisella tularensis Live Vaccine Strain
Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. It is capable of escaping from the phagosome, replicating to high numbers in the cytosol, and inducing apoptosis in macrophages of a variety of hosts. F. tularensis has received significant atte...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1539594/ https://ncbi.nlm.nih.gov/pubmed/16861631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00666-06 |
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