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Construction and Characterization of an Attenuated Purine Auxotroph in a Francisella tularensis Live Vaccine Strain

Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. It is capable of escaping from the phagosome, replicating to high numbers in the cytosol, and inducing apoptosis in macrophages of a variety of hosts. F. tularensis has received significant atte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pechous, Roger, Celli, Jean, Penoske, Renee, Hayes, Stanley F., Frank, Dara W., Zahrt, Thomas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539594/
https://ncbi.nlm.nih.gov/pubmed/16861631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00666-06
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