Immunotargeting with CD154 (CD40 Ligand) Enhances DNA Vaccine Responses in Ducks

Engagement of CD154 on activated T cells with CD40 on antigen-presenting cells (APCs) potentiates adaptive immune responses in mammals. Soluble multimeric forms of CD154 have been used as an adjuvant or in immunotargeting strategies to enhance vaccine responses. The objective of our study was to exa...

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Bibliografiske detaljer
Main Authors: Gares, Sheryl L., Fischer, Karl P., Congly, Stephen E., Lacoste, Stacey, Addison, William R., Tyrrell, D. Lorne, Gutfreund, Klaus S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Vaccine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539120/
https://ncbi.nlm.nih.gov/pubmed/16893998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00080-06
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