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Sequence Variation in a Newly Identified HLA-B35-Restricted Epitope in the Influenza A Virus Nucleoprotein Associated with Escape from Cytotoxic T Lymphocytes

Here, we describe a new HLA-B*3501-restricted cytotoxic T lymphocyte (CTL) epitope in the influenza A virus (H3N2) nucleoprotein, which was found to exhibit a high degree of variation at nonanchor residues. The influenza virus variants emerged in chronological order, and CTLs directed against old va...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Boon, A. C. M., de Mutsert, G., Graus, Y. M. F., Fouchier, R. A. M., Sintnicolaas, K., Osterhaus, A. D. M. E., Rimmelzwaan, G. F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836437/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2567-2572.2002
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