Altering the Expression Kinetics of VP5 Results in Altered Virulence and Pathogenesis of Herpes Simplex Virus Type 1 in Mice

While many herpes simplex virus (HSV) structural proteins are expressed with strict-late kinetics, the HSV virion protein 5 (VP5) is expressed as a “leaky-late” protein, such that appreciable amounts of VP5 are made prior to DNA replication. Our goal has been to determine if leaky-late expression of...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Tran, Robert K., Lieu, Pauline T., Aguilar, Santiago, Wagner, Edward K., Bloom, David C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836397/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2199-2205.2002
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