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Altering the Expression Kinetics of VP5 Results in Altered Virulence and Pathogenesis of Herpes Simplex Virus Type 1 in Mice

While many herpes simplex virus (HSV) structural proteins are expressed with strict-late kinetics, the HSV virion protein 5 (VP5) is expressed as a “leaky-late” protein, such that appreciable amounts of VP5 are made prior to DNA replication. Our goal has been to determine if leaky-late expression of...

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Vydáno v:J Virol
Hlavní autoři: Tran, Robert K., Lieu, Pauline T., Aguilar, Santiago, Wagner, Edward K., Bloom, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2002
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2199-2205.2002
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