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Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease

Neuronal nicotinic AChRs (nAChRs) are implicated in the pathogenesis of diverse neurological disorders and in the regulation of small-cell lung carcinoma growth. Twelve subunits have been identified in vertebrates, and mutations of one are recognized in a rare form of human epilepsy. Mice with genet...

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Bibliografiske detaljer
Main Authors: Lennon, Vanda A., Ermilov, Leonid G., Szurszewski, Joseph H., Vernino, Steven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153771/
https://ncbi.nlm.nih.gov/pubmed/12639997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317429
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