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Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease

Neuronal nicotinic AChRs (nAChRs) are implicated in the pathogenesis of diverse neurological disorders and in the regulation of small-cell lung carcinoma growth. Twelve subunits have been identified in vertebrates, and mutations of one are recognized in a rare form of human epilepsy. Mice with genet...

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Autori principali: Lennon, Vanda A., Ermilov, Leonid G., Szurszewski, Joseph H., Vernino, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153771/
https://ncbi.nlm.nih.gov/pubmed/12639997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317429
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