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Monoclonal antibodies to the idiotypic determinants of a human IgG paraprotein: evidence for complexity of the anti-idiotype response.
BALB/c mice were immunized with a human gamma 2k paraprotein and hybridomas prepared by the Kohler & Milstein technique. Ten hybridoma clones producing high levels of antibody competed reacting specificity with the immunogen were isolated. Six of the monoclonal antibodies competed strongly with...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1536580/ https://ncbi.nlm.nih.gov/pubmed/6177459 |
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