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Monoclonal antibodies to the idiotypic determinants of a human IgG paraprotein: evidence for complexity of the anti-idiotype response.

BALB/c mice were immunized with a human gamma 2k paraprotein and hybridomas prepared by the Kohler & Milstein technique. Ten hybridoma clones producing high levels of antibody competed reacting specificity with the immunogen were isolated. Six of the monoclonal antibodies competed strongly with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ling, N R, Lowe, J, Jefferis, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536580/
https://ncbi.nlm.nih.gov/pubmed/6177459
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