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Pertussis vaccine inhibits immune insulitis induced with streptozotocin.
Normally, the injection of streptozotocin (STZ) at a lower dose (60 mg/kg body weight) to young (45 days old) CD-1 male mice produces a sustained hyperglycemia with the concomitant development of hypoinsulinemia and immune insulitis in the pancreas, both of which lead to insulin-dependent diabetes (...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1982
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1536449/ https://ncbi.nlm.nih.gov/pubmed/6213327 |
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