Abbreviated incubation times for human prions in mice expressing a chimeric mouse–human prion protein transgene

Transgenic (Tg) mouse lines that express chimeric mouse–human prion protein (PrP), designated MHu2M, are susceptible to prions from patients with sporadic Creutzfeldt–Jakob disease (sCJD). With the aim of decreasing the incubation time to fewer than 200 days, we constructed transgenes in which one o...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Proc Natl Acad Sci U S A
المؤلفون الرئيسيون:	Korth, Carsten, Kaneko, Kiyotoshi, Groth, Darlene, Heye, Norbert, Telling, Glenn, Mastrianni, James, Parchi, Piero, Gambetti, Pierluigi, Will, Robert, Ironside, James, Heinrich, Cornelia, Tremblay, Patrick, DeArmond, Stephen J., Prusiner, Stanley B.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	National Academy of Sciences 2003
الموضوعات:	Biological Sciences
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12684540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2627989100
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!