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Rep and PriA helicase activities prevent RecA from provoking unnecessary recombination during replication fork repair

The rescue of replication forks stalled on the template DNA was investigated using an assay for synthetic lethality that provides a visual readout of cell viability and permits investigation of why certain mutations are lethal when combined. The results presented show that RecA and other recombinati...

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Autores principales: Mahdi, Akeel A., Buckman, Carol, Harris, Lynda, Lloyd, Robert G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536063/
https://ncbi.nlm.nih.gov/pubmed/16882986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.382306
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