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Rep and PriA helicase activities prevent RecA from provoking unnecessary recombination during replication fork repair

The rescue of replication forks stalled on the template DNA was investigated using an assay for synthetic lethality that provides a visual readout of cell viability and permits investigation of why certain mutations are lethal when combined. The results presented show that RecA and other recombinati...

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Hlavní autoři: Mahdi, Akeel A., Buckman, Carol, Harris, Lynda, Lloyd, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536063/
https://ncbi.nlm.nih.gov/pubmed/16882986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.382306
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