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Processing, localization, and requirement of human separase for normal anaphase progression
In all eukaryotes, anaphase is triggered by the activation of a protease called separase. Once activated, separase cleaves a subunit of cohesin, a complex that links replicated chromatids before anaphase. Separase and cohesin are conserved from yeasts to humans. Although the machinery for dissolving...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153597/ https://ncbi.nlm.nih.gov/pubmed/12672959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730733100 |
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