Severe combined immunodeficient (SCID) mice: a model for investigating human thyroid autoantibody synthesis.

We have studied the ability of lymphocytes from the blood, thyroid and lymph nodes of patients with autoimmune thyroid disease (AITD) to produce autoantibodies to thyroglobulin (Tg) and/or thyroid peroxidase (TPO) in SCID mice. Human IgG class Tg and/or TPO antibodies were detectable in plasma from...

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Détails bibliographiques
Auteurs principaux: Macht, L, Fukuma, N, Leader, K, Sarsero, D, Pegg, C A, Phillips, D I, Yates, P, McLachlan, S M, Elson, C, Rees Smith, B
Format: Artigo
Langue:Inglês
Publié: 1991
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535369/
https://ncbi.nlm.nih.gov/pubmed/2015711
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