Severe combined immunodeficient (SCID) mice: a model for investigating human thyroid autoantibody synthesis.

We have studied the ability of lymphocytes from the blood, thyroid and lymph nodes of patients with autoimmune thyroid disease (AITD) to produce autoantibodies to thyroglobulin (Tg) and/or thyroid peroxidase (TPO) in SCID mice. Human IgG class Tg and/or TPO antibodies were detectable in plasma from...

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Autors principals: Macht, L, Fukuma, N, Leader, K, Sarsero, D, Pegg, C A, Phillips, D I, Yates, P, McLachlan, S M, Elson, C, Rees Smith, B
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535369/
https://ncbi.nlm.nih.gov/pubmed/2015711
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