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Lack of T cell oligoclonality in enzyme-digested synovial tissue and in synovial fluid in most patients with rheumatoid arthritis.

The dominant presence of specific T-cell populations in the rheumatoid joint as detected by Southern blot analysis of T cell receptor (TCR) gene rearrangements would indicate local antigen recognition and T cell proliferation. We therefore studied TCR beta chain gene rearrangements using a C beta 2...

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Autors principals: Van Laar, J M, Miltenburg, A M, Verdonk, M J, Daha, M R, De Vries, R R, Van den Elsen, P J, Breedveld, F C
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535313/
https://ncbi.nlm.nih.gov/pubmed/1848487
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