CDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response.

T lymphocytes reactive with as yet undefined joint-localized foreign or autoantigens may be important in the pathogenesis of RA. Molecular studies demonstrating skewed T cell antigen receptor (TCR) variable gene usage and selective expansion of particular T cell clones within the synovial compartmen...

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Dettagli Bibliografici
Autori principali: Li, Y, Sun, G R, Tumang, J R, Crow, M K, Friedman, S M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC330088/
https://ncbi.nlm.nih.gov/pubmed/7989613
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