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Statins stimulate arachidonic acid release and prostaglandin I(2 )production in rat liver cells

Statins inhibit 3-hydroxy-3-methylglutaryl (HMG-CoA) reductase, the rate limiting step in cholesterol synthesis. They are, therefore, used clinically to lower cholesterol and prevent atherosclerosis. Statins have beneficial effects on multiple organ systems. Some of these effects are found in the ab...

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Detalhes bibliográficos
Autor principal: Levine, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153527/
https://ncbi.nlm.nih.gov/pubmed/12689340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-2-1
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