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Tetrandrine and thapsigargin release arachidonic acid from cells in culture and stimulate prostacyclin production in rat liver cells, but may do so by different pathways
BACKGROUND: Tetrandrine inhibits tumor cell proliferation and demonstrates chemoprevention in cancer models. Speculation on the association between its effects on K(+ )and Ca(2+ )channels and cancer chemoprevention has been made. Thapsigargin also affects K(+ )and Ca(2+ )conductance. Thapsigargin, h...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180457/ https://ncbi.nlm.nih.gov/pubmed/15978132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-5-12 |
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