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Rapid clearance of the lupus antigen Sm is delayed by autoantibody: a possible mechanism of autoimmunity perpetuation.

Sm ribonucleoprotein complex was immunopurified and labelled with 125I. After i.v. injection into normal mice 125I-Sm was cleared with a half life of less than 3 min, mainly to the liver (54% at 15 min). With time there was a progressive reduction in liver uptake (13.3% at 1 h), and this was associa...

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Hlavní autoři: Field, M, Melsom, R D, Brennan, F M, Williams, D G, Schreiber, L, McCarthy, D A, Maini, R N, Nelsom, R D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534824/
https://ncbi.nlm.nih.gov/pubmed/2612056
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