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Autoimmune kidney disease in MRL/Mp-lpr/lpr mice inhibited by OK-432, a streptococcal preparation.

Autoimmune MRL/Mp-lpr/lpr (MRL/l) mice were treated with the immunostimulating anti-cancer drug OK-432 (a streptococcal preparation), a potent inducer of tumour necrosis factor. Treatment was initiated at 8 weeks of age, before the onset of the autoimmune disease. OK-432 prevented the development of...

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Autores principales: Mihara, M, Ohsugi, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534609/
https://ncbi.nlm.nih.gov/pubmed/2805413
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