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Inhibition of IL-4 receptor up-regulation on B cells by antisense oligodeoxynucleotide suppresses IL-4-induced human IgE production.

IL-4 is shown to up-regulate its own receptor (IL-4R) on human lymphocytes, but the functional significance of up-regulated IL-4R is not clear regarding IgE production. This study investigated the possible role of IL-4-induced up-regulation of IL-4R on B cells in the induction of human IgE synthesis...

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Bibliografske podrobnosti
Main Authors: Ikizawa, K, Kajiwara, K, Koshio, T, Matsuura, N, Yanagihara, Y
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534458/
https://ncbi.nlm.nih.gov/pubmed/7539723
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