Specific inhibition of IgE antibody production by an antisense oligodeoxynucleotide oligomer (Oligostick).

We have investigated the ability of an antisense oligonucleotide (ASE-1) to specifically inhibit IgE synthesis by a human myeloma cell line, U266. ASE-1 inhibited IgE production in a concentration-dependent manner, as assessed by isotype-specific ELISA measurement of immunoglobulin in myeloma cell s...

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Hlavní autoři: Hall, T J, Brostoff, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421710/
https://ncbi.nlm.nih.gov/pubmed/1478691
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