T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation

The central role of type-2 helper T (Th2) cells in the development of allergic responses and immune responses against helminthic parasites is well documented. The differentiation of Th2 cells from naive T cells requires both the recognition of antigen by T cell antigen receptors (TCR) and the activa...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Yamashita, Masakatsu, Kimura, Motoko, Kubo, Masato, Shimizu, Chiori, Tada, Tomio, Perlmutter, Roger M., Nakayama, Toshinori
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1999
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.1024
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