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Activation of human complement by mouse and mouse/human chimeric monoclonal antibodies.

The complement (C)-activating capabilities in human serum of 32 mouse and 10 mouse/human chimeric MoAbs of different isotypes, and their fragments, were tested in vitro. Activation of C via the classical pathway (CP) was performed in 1% factor D-deficient serum in gelatin containing Veronal buffer i...

詳細記述

保存先:
書誌詳細
主要な著者: Seino, J, Eveleigh, P, Warnaar, S, van Haarlem, L J, van Es, L A, Daha, M R
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534236/
https://ncbi.nlm.nih.gov/pubmed/8222320
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