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Failure of IgG production due to a defect in the opening of the chromatin structure of I gamma 1 region in a patient with IgG and IgA deficiency.

Patients with common variable immunodeficiency (CVID) display reduced levels of two or all three of the major immunoglobulin isotypes, and the deficiency is characterized by failure of B cells to differentiate into plasma cells in many cases. A patient (14 years old, female) showed normal serum IgM...

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Detalhes bibliográficos
Main Authors: Kondo, N, Inoue, R, Kasahara, K, Kaneko, H, Kameyama, T, Orii, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534132/
https://ncbi.nlm.nih.gov/pubmed/7813107
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