Polymorphisms in estrogen-metabolizing and estrogen receptor genes and the risk of developing breast cancer among a cohort of women with benign breast disease

BACKGROUND: A cohort study was conducted to examine the role of genetic polymorphisms in three estrogen metabolizing enzymes (COMT, CYP1A1, CYP1B1) and the two estrogen receptors (ESR1, ESR2) in the progression of benign breast disease (BBD) to breast cancer. METHODS: Among participants in an ongoin...

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Main Authors: Gallicchio, Lisa, Berndt, Sonja I, McSorley, Meghan A, Newschaffer, Craig J, Thuita, Lucy W, Argani, Pedram, Hoffman, Sandra C, Helzlsouer, Kathy J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534058/
https://ncbi.nlm.nih.gov/pubmed/16808847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-173
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