Alcohol Dehydrogenase Genetic Polymorphisms, Low-to-Moderate Alcohol Consumption and Risk of Breast Cancer

BACKGROUND: In vitro, human isoenzymes encoded by genes homozygous for the ADH1C*1 or ADH1B*2 alleles metabolize ethanol to acetaldehyde at a faster rate than those homozygous for the ADH1C*2 or ADH1B*1 allele. Because alcohol is a known risk factor for breast cancer, we evaluated the joint associat...

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Auteurs principaux: Visvanathan, Kala, Crum, Rosa M., Strickland, Paul T., You, Xiaojun, Ruczinski, Ingo, Berndt, Sonja I., Alberg, Anthony J., Hoffman, Sandra C., Comstock, George W., Bell, Douglas A., Helzlsouer, Kathy J.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787101/
https://ncbi.nlm.nih.gov/pubmed/17295732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2006.00334.x
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