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Differences in the evolutionary history of disease genes affected by dominant or recessive mutations

BACKGROUND: Global analyses of human disease genes by computational methods have yielded important advances in the understanding of human diseases. Generally these studies have treated the group of disease genes uniformly, thus ignoring the type of disease-causing mutations (dominant or recessive)....

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Detalhes bibliográficos
Main Authors: Furney, Simon J, Albà, M Mar, López-Bigas, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534034/
https://ncbi.nlm.nih.gov/pubmed/16817963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-165
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