Centering, scaling, and transformations: improving the biological information content of metabolomics data

BACKGROUND: Extracting relevant biological information from large data sets is a major challenge in functional genomics research. Different aspects of the data hamper their biological interpretation. For instance, 5000-fold differences in concentration for different metabolites are present in a meta...

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Hlavní autoři: van den Berg, Robert A, Hoefsloot, Huub CJ, Westerhuis, Johan A, Smilde, Age K, van der Werf, Mariët J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534033/
https://ncbi.nlm.nih.gov/pubmed/16762068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-142
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