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Integrin β3-mediated Src activation regulates apoptosis in IEC-6 cells via Akt and STAT3

Intestinal epithelial (IEC-6) cells are resistant to apoptosis following the inhibition of ODC (ornithine decarboxylase) and subsequent polyamine depletion. The depletion of polyamines rapidly activates NF-κB (nuclear factor κB) and STAT3 (signal transducer and activator of transcription 3), which i...

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Autori principali: Bhattacharya, Sujoy, Ray, Ramesh M., Johnson, Leonard R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533302/
https://ncbi.nlm.nih.gov/pubmed/16669788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060256
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