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Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing.

Carcinogenicity testing is indispensable for identifying environmental carcinogens and for evaluating the safety of drugs in the process of development. Conventional 2-year rodent bioassays are one of the most resource-consuming tests in terms of animals, time, and costs. Development of rapid carcin...

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Autors principals: Yamamoto, S, Urano, K, Koizumi, H, Wakana, S, Hioki, K, Mitsumori, K, Kurokawa, Y, Hayashi, Y, Nomura, T
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533281/
https://ncbi.nlm.nih.gov/pubmed/9539005
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