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APLIP1, a Kinesin Binding JIP-1/JNK Scaffold Protein, Influences the Axonal Transport of Both Vesicles and Mitochondria in Drosophila

In a genetic screen for Kinesin heavy chain (Khc)-interacting proteins, we identified APLIP1, a neuronally expressed Drosophila homolog of JIP-1, a JNK scaffolding protein [1]. JIP-1 and its homologs have been proposed to act as physical linkers between kinesin-1, which is a plus-end-directed microt...

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Sonraí Bibleagrafaíochta
Main Authors: Horiuchi, Dai, Barkus, Rosemarie V., Pilling, Aaron D., Gassman, Andrew, Saxton, William M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1532932/
https://ncbi.nlm.nih.gov/pubmed/16332540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2005.10.047
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