A Constitutively Active Variant of the Quorum-Sensing Regulator LuxO Affects Protease Production and Biofilm Formation in Vibrio cholerae

Vibrio cholerae normally inhabits aquatic habitats but can cause a severe diarrheal illness in humans. Its arsenal of virulence factors includes a secreted hemagglutinin (HA) protease. An HA protease-deficient mutant of V. cholerae was isolated and designated E7946 mpc. E7946 mpc was found to contai...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Vance, Russell E., Zhu, Jun, Mekalanos, John J.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Molecular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2571-2576.2003
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